Physicians discovered that patients responded readily to infusions of plasma when given promptly after they sustained spontaneous joint and muscle bleeding. Victoria's sixth child, Louise, died without issue. सीधे इस पर जाएँ. In 1926 Finnish physician Erik von Willebrand published a paper describing what he called “pseudohemophilia,” a bleeding disorder affecting men and women equally. Factor products became safer as tighter screening methods were implemented and advanced methods of viral inactivation were used. Hemophilia is commonly known as the “Royal disease” because the disease has plagued many royals. In 1947, Dr. Alfredo Pavlovsky, a doctor in Buenos Aires, Argentina, distinguished two types of hemophilia in his lab—A and B. Blood disorders can also affect the liquid portion of blood, called plasma. It’s an inherited disease that’s usually passed from mother to son. Leopold (1853–1884), Victoria's eighth child, was the first member of the family to manifest haemophilia; he died at age 30 from bleeding after a minor fall,[5] only two years after marrying Princess Helena of Waldeck and Pyrmont.